Daniel Hunter
I grew up in the South-East of the UK and studied at the University of Sussex, in the lab of Dr Andrew Penn, as part of my Masters Diploma. Here, we investigated the pathological mechanisms by which single missense mutations in NMDA receptor subunit-coding genes can induce variable epileptic phenotypes and associated intellectual disability, focusing on receptor trafficking, synapse maturation and neurotoxicity. I am particularly fascinated by the way that disruption of synaptic function – at the level of individual receptors – can translate throughout the levels of neuroscience, from the molecular through to a behavioural or clinical phenotype.